Newsletter 149
June 4, 2007

The NIH X-Ray Diffraction Interest Group

Newsletter web site: http://mcl1.ncifcrf.gov/nihxray

The 37th Mid-Atlantic Macromolecular Crystallography Meeting
7-9 June 2007, Charlottesville, Virginia, USA

The 2007 Meeting of the American Crystallographic Associstion
21-26 July 2007, Salt Lake City, UT, USA

The 9th International Conference on Biology and Synchrotron Radiation
13-17 August 2007, Manchester, England

The 21st Congress of the Internatinal Union of Crystallography
23 - 31 August 2008, Osaka, Japan

Item 1: May 2007 Publications by Members

1: Phan J, Tropea JE, Waugh DS.
 Structure-assisted discovery of Variola major H1 phosphatase inhibitors.
Acta Crystallogr D Biol Crystallogr. 2007 Jun;63(Pt 6):698-704. PMID: 17505108
   
2: Ziolkowska NE, Shenoy SR, O'Keefe BR, McMahon JB, Palmer KE, Dwek RA,
Wormald MR, Wlodawer A.
 Crystallographic, thermodynamic, and molecular modeling studies 
of the mode obinding of oligosaccharides to the potent antiviral protein griffithsin.
Proteins. 2007 May 15;67(3):661-70. PMID: 17340634

Item 2: Tips and Tricks

Tantalum Cluster [(Ta₆Br₁₂)²⁺] Derivatization Kit - Available
Check out http://www.jenabioscience.com/cms/en/1/catalog/1166 for information.

Click for Introduction and tips and tricks in Pre-crystallization modification, Crystallization, Post-crystallization treatment, Derivatization, Diffraction, Symmetry, Structure Solution, Structure Refinement, and Structure Analysis.

Item 3: Topic Discussion

Click for previous discussions on: Low Resolution Crystallography, PHASER, HKL2000, Parallel Protein Expression, Structural Genomics, NCS, Missing Atoms, Trends in Crystallography, and Absorption Correction.

2005)

Part 1: "How to read international tables?"

Part 2: "Data collection strategy" and "Twinning"

"Phasing methods - a general introduction to all methods"

Part 3: "SAD phasing, Quick halide soaking, and Radiation damage

with possible use of it for phasing"

This site is maintained by Dr. Xinhua Ji (jix@ncifcrf.gov) on the NCI-CCR-MCL server (http://mcl1.ncifcrf.gov).