Newsletter 146
April 23, 2007

The NIH X-Ray Diffraction Interest Group

Newsletter web site: http://mcl1.ncifcrf.gov/nihxray

The 37th Mid-Atlantic Macromolecular Crystallography Meeting
7-9 June 2007, Charlottesville, Virginia, USA

The 2007 Meeting of the American Crystallographic Associstion
21-26 July 2007, Salt Lake City, UT, USA

The 9th International Conference on Biology and Synchrotron Radiation
13-17 August 2007, Manchester, England

The 21st Congress of the Internatinal Union of Crystallography
23 - 31 August 2008, Osaka, Japan

Item 1: March 2007 Publications by Members:

1:  Boeggeman E, Ramakrishnan B, Kilgore C, Khidekel N, Hsieh-Wilson LC, Simpson
JT, Qasba PK. 
 Direct Identification of Nonreducing GlcNAc Residues on N-Glycans of
Glycoproteins Using a Novel Chemoenzymatic Method.
Bioconjug Chem. 2007 Mar 20; [Epub ahead of print] PMID: 17370997 
  
2:  Plested AJ, Mayer ML. 
 Structure and mechanism of kainate receptor modulation by anions.
Neuron. 2007 Mar 15;53(6):829-41. PMID: 17359918
  
3:  Liu Y, Prasad R, Beard WA, Kedar PS, Hou EW, Shock DD, Wilson SH. 
 Coordination of steps in single-nucleotide base excision repair mediated by
apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta.
J Biol Chem. 2007 Mar 12; [Epub ahead of print] PMID: 17355977 
  
4:  Cai M, Huang Y, Suh JY, Louis JM, Ghirlando R, Craigie R, Clore GM. 
 Solution NMR structure of the barrier-to-autointegration factor/emerin complex.
J Biol Chem. 2007 Mar 13; [Epub ahead of print] PMID: 17355960 
  
5:  Dolman NP, More JC, Alt A, Knauss JL, Pentikainen OT, Glasser CR, Bleakman
D, Mayer ML, Collingridge GL, Jane DE. 
 Synthesis and Pharmacological Characterization of N(3)-Substituted Willardiine
Derivatives: Role of the Substituent at the 5-Position of the Uracil Ring in the
Development of Highly Potent and Selective GLU(K5) Kainate Receptor Antagonists.
J Med Chem. 2007 Apr 5;50(7):1558-1570. Epub 2007 Mar 10. PMID: 17348638
  
6:  Ziolkowska NE, Shenoy SR, O'keefe BR, McMahon JB, Palmer KE, Dwek RA,
Wormald MR, Wlodawer A. 
 Crystallographic, thermodynamic, and molecular modeling studies of the mode of
binding of oligosaccharides to the potent antiviral protein griffithsin.
Proteins. 2007 Mar 5;67(3):661-670 [Epub ahead of print] PMID: 17340634

Item 2: Tips and Tricks

Click for Introduction and tips and tricks in Pre-crystallization modification, Crystallization, Post-crystallization treatment, Derivatization, Diffraction, Symmetry, Structure Solution, Structure Refinement, and Structure Analysis.

Item 3: Topic Discussion

Click for previous discussions on: Low Resolution Crystallography, PHASER, HKL2000, Parallel Protein Expression, Structural Genomics, NCS, Missing Atoms, Trends in Crystallography, and Absorption Correction.

2005)

Part 1: "How to read international tables?"

Part 2: "Data collection strategy" and "Twinning"

"Phasing methods - a general introduction to all methods"

Part 3: "SAD phasing, Quick halide soaking, and Radiation damage

with possible use of it for phasing"

This site is maintained by Dr. Xinhua Ji (jix@ncifcrf.gov) on the NCI-CCR-MCL server (http://mcl1.ncifcrf.gov).