Item 1: September 2005 Publications by Members:
 

1:  Li M, Rasulova F, Melnikov EE, Rotanova TV, Gustchina A, Maurizi MR, Wlodawer A.
 Crystal structure of the N-terminal domain of E. coli Lon protease.
Protein Sci. 2005 Sep 30; PMID: 16199667

2:  Zhou T, Hamer DH, Hendrickson WA, Sattentau QJ, Kwong PD.
 Interfacial metal and antibody recognition.
Proc Natl Acad Sci U S A. 2005 Sep 29; PMID: 16195378

3:  Laronde-Leblanc N, Wlodawer A.
 A family portrait of the RIO kinases.
J Biol Chem. 2005 Sep 22; PMID: 16183636

4:  Laronde-Leblanc N, Wlodawer A.
 The RIO kinases: An atypical protein kinase family required for ribosome
biogenesis and cell cycle progression.
Biochim Biophys Acta. 2005 Sep 20; PMID: 16182620

5:  Nallamsetty S, Waugh DS.
 Solubility-enhancing proteins MBP and NusA play a passive role in the folding of their fusion partners.
Protein Expr Purif. 2005 Sep 14; PMID: 16168669

6:  Dimitrov AS, Louis JM, Bewley CA, Clore GM, Blumenthal R.
 Conformational Changes in HIV-1 gp41 in the Course of HIV-1 Envelope
Glycoprotein-Mediated Fusion and Inactivation.
Biochemistry. 2005 Sep 20;44(37):12471-12479. PMID: 16156659

7:  Bradley CM, Ronning DR, Ghirlando R, Craigie R, Dyda F.
 Structural basis for DNA bridging by barrier-to-autointegration factor.
Nat Struct Mol Biol. 2005 Oct;12(10):935-6. PMID: 16155580

8:  Im YJ, Raychaudhuri S, Prinz WA, Hurley JH.
 Structural mechanism for sterol sensing and transport by OSBP-related proteins.
Nature. 2005 Sep 1;437(7055):154-8. PMID: 16136145

9:  Ramagopal UA, Dauter Z, Thirumuruhan R, Fedorov E, Almo SC.
 Radiation-induced site-specific damage of mercury derivatives: phasing and implications.
Acta Crystallogr D. 2005 Sep;61(Pt 9):1289-98. PMID: 16131763

10:  Longo A, Leonard CW, Bassi GS, Berndt D, Krahn JM, Hall TM, Weeks KM.
 Evolution from DNA to RNA recognition by the bI3 LAGLIDADG maturase.
Nat Struct Mol Biol. 2005 Sep;12(9):779-87. PMID: 16116439

11:  Vaisman A, Ling H, Woodgate R, Yang W.
 Fidelity of Dpo4: effect of metal ions, nucleotide selection and
pyrophosphorolysis.
EMBO J. 2005 Sep 7;24(17):2957-67. PMID: 16107880

12:  Lee K, Boovanahalli SK, Nam KY, Kang SU, Lee M, Phan J, Wu L, Waugh DS, Zhang ZY, No KT, Lee JJ, Burke TR Jr.
 Synthesis of tripeptides as potent Yersinia protein tyrosine phosphatase
inhibitors.
Bioorg Med Chem Lett. 2005 Sep 15;15(18):4037-42. PMID: 16039123

13:  Ferguson SS, Chen Y, LeCluyse EL, Negishi M, Goldstein JA.
 Human CYP2C8 is transcriptionally regulated by the nuclear receptors
constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.
Mol Pharmacol. 2005 Sep;68(3):747-57. PMID: 15933212

14:  Chen Y, Kissling G, Negishi M, Goldstein JA.
 The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4alpha to synergistically activate the human CYP2C9 promoter.
J Pharmacol Exp Ther. 2005 Sep;314(3):1125-33. PMID: 15919766
 

Item 2: Tips and Tricks

This section is always open for contributions. Click for Introduction and tips and tricks in Crystallization, Derivatization, Diffraction, Symmetry, Structure Solution, Structure Refinement, and Structure Analysis.

Recommended Review: "Post-crystallization treatments for improving diffraction quality of protein crystals" by Begona Hera and Jennifer L. Martin

Item 3: Topic Discussion

PHASER: MR with Maximum Likelihood

Click for previous discussions on: PHASER, HKL2000, Parallel Protein Expression, Structural Genomics, NCS, Missing Atoms, Trends in Crystallography, and Absorption Correction.

Item 4: Lectures

Dr. Zbigniew Dauter's Lectures at the NIH (03/29-31)