HIVdb: Table of Ligand-Enzyme Complexes

System	PDB File	HIVdb File	Company or Laboratory	Quality	Year	Inhibitor (Type)
HIV-1 PR (BH10 isolate) with substrate (model)	1hvp	hiv1nci	ABL-BRP, NCI Frederick	*******	1989	N/A
HIV-1 PR (NY5 isolate)unliganded	2hvp	hiv1msd	Merck, Sharp and Dohme Res. Lab	*******	1989	N/A
HIV-1 PR (ARV2/SF2 isolate) unliganded	3hvp	hiv2nci	ABL-BRP, NCI Frederick	*******	1989	N/A
HIV-1 PR (HXB2 isolate) unliganded	3phv	hiv1bcl	Birkbeck College, Laboratory of Molecular Biology, London	*******	1989	N/A
HIV-1 PR (synthetic enzyme) with inhibitor MVT101	4hvp	hiv3nci	ABL-BRP, NCI Frederick	*******	1989	MVT101 (Reduced amide isostere)
HIV-1 PR (BH10 isolate) with inhibitor A74704	9hvp	hiv1abb	Abbott Laboratories Dept. of CAMD	*******	1990	A74704 (hydroxyethylene isostere)
HIV-1 PR (synthetic enzyme) with inhibitor JG365	7hvp	hiv4nci	ABL-BRP, NCI Frederick	*******	1990	JG365 (hydroxyethylamine isostere)
HIV-1 PR (NY5 isolate) with acetyl-pepstatin	5hvp	hiv2msd	Merck Sharp and Dohme Res. Lab	*******	1990	(Statine izostere)
HIV-2 PR (ROD isolate) with renin inhibitor H261 (model)	2phv	hiv5nci	ABL-BRP, NCI Frederick	*******	1991	H261 (hydroxyethylene isostere)
HIV-2 PR (ROD isolate) with acetyl-pepstatin (model)	1phv	hiv6nci	ABL-BRP, NCI Frederick	*******	1991	Acetyl-Pepstatin
HIV-1 PR (NY5 isolate) with pseudo C2 - symmetry inhibitor L-700,417	4phv	hiv3msd	Merck Sharp and Dohme Res. Lab	*******	1991	L-700,417 (hydroxyethylene isostere)
HIV-1 PR (synthetic enzyme) with inhibitor U-85548E	8hvp	hiv7nci	ABL-BRP, NCI Frederick	*******	1991	U-85548E (hydroxyethylene isostere)
HIV-1 PR (BRU isolate) unliganded	1hhp	hiv1pip	Institut Pasteur, Paris	*******	1991	N/A
HIV-1 PR (BH10 isolate) with inhibitor SKF 108738	1hef	hiv1skb	SmithKline Beecham Pharmaceuticalss	*******	1992	SKF 108738 (hydroxyethylene isostere)
HIV-1 PR (BH10 isolate) with inhibitor SKF 107457	1heg	hiv2skb	SmithKline Beecham Pharmaceuticalss	*******	1992	SKF 107457 (hydroxyethylene isostere)
HIV-1 PR (BH10 isolate) with hydroxyethylene inhibitor	1aaq	hiv3skb	SmithKline Beecham Pharmaceuticalss	*******	1992	(hydroxyethylene isostere)
HIV-1 PR (isolate unknown) with dihydroxyethylene inhibitor U75875	1hiv	hiv8nci	ABL-BRP, NCI Frederick	*******	1992	U75875 (dihydroxyethylene isostere)
HIV-1 PR (BH10 isolate) with C2 - symmetric phosphinate inhibitor	1hos	hiv4skb	SmithKline Beecham Pharmaceuticalss	*******	1993	SB204144 (perfectly symmetrical phosphinate inhibitor)
HIV-1 PR (BH10 isolate) with penicillin - derived C2 - symmetric inhibitor	1hte	hiv1glx	Glaxo Group Research Limited	*******	1993	GR123976 (penicillin-derived C2-symmetric inhibitor)
HIV-1 PR (BH10 isolate) with penicillin - derived C2 - symmetric inhibitor	1htf	hiv2glx	Glaxo Group Research Limited	*******	1993	GR126045 (penicillin-derived C2-symmetric inhibitor)
HIV-2 PR (ROD isolate) with inhibitor BILA-398	2mip	hiv1bip	Boehringer Ingelheim Pharmaceuticalss	*******	1993	BILA-398 (reduced amide isostere)
SIV PR (mutant S4H, from macaque monkeys, recombinant form SIV = MAC = 239, plasmid SOD) with irreversible nonpeptide inhibitor EPNP	2sam	hiv1ucs	University of California San Francisco	*******	1993	EPNP (epoxy inhibitor)
HIV-2 PR (isolate unknown) K57L mutant with inhibitor U75875	1ivp	hiv1ulk	Upjohn Company, Kalamazoo	*******	1993	U75875 (dihydroxyethylene isostere)
HIV-2 PR (isolate unknown) K57L mutant with inhibitor U92163	1ivq	hiv2ulk	Upjohn Company, Kalamazoo	*******	1993	U92163 (hydroxyethylene isostere)
SIV PR (MAC 251 isolate) with inhibitor SKF107457	1siv	hiv5skb	SmithKline Beecham Pharmaceuticalss	*******	1993	SKF107457 (hydroxyethylene isostere)
HIV-1 PR (BH10 isolate) with inhibitor SB206343	1hps	hiv6skb	SmithKline Beecham Pharmaceuticalss	*******	1994	SB 206343 (hydroxyethylene isostere)
HIV-1 PR (NY5 isolate) with inhibitor L-735,524 (MK639) [CRIXIVAN (Indinavir)]	1hsg	hiv4msd	Merck & Co., Inc.	*******	1994	L-735,524; MK-639, Indinavir,Crixivan (hydroxyethylene isostere)
HIV-2 PR (ROD isolate) with inhibitor L-735,524	1hsh	hiv5msd	Merck Sharp and Dohme Res. Lab	*******	1994	L-735,524,MK-639,Indinavir,Crixivan (hydroxyethylene isostere)
HIV-2 PR (ROD isolate) without inhibitor	1hsi	hiv6msd	Merck Sharp and Dohme Res. Lab	*******	1994	N/A
HIV-1 PR (BH10 isolate) with inhibitor SB 203386	1sbg	hiv7skb	SmithKline Beecham Pharmaceuticalss	*******	1994	SB 203386 (hydroxyethylene isostere)
HIV-1 PR (BH10 isolate) with C2 - symmetry - based diol inhibitor A77003(R,S)	1hvi	hiv9nci	SAIC, NCI Frederick	*******	1994	A77003 (C2 symmetry-based diol isostere)
HIV-1 PR (BH10 isolate) with C2 - symmetry - based diol inhibitor A78791(S,-)	1hvj	hiv10nci	SAIC, NCI Frederick	*******	1994	A78791 (C2 symmetry-based diol isostere)
HIV-1 PR (BH10 isolate) with C2 - symmetry - based diol inhibitor A76928(S,S)	1hvk	hiv11nci	SAIC, NCI Frederick	*******	1994	A76928 (C2 symmetry-based diol isostere)
HIV-1 PR (BH10 isolate) with C2 - symmetry - based diol inhibitor A76889(R,R)	1hvl	hiv12nci	SAIC, NCI Frederick	*******	1994	A76889 (C2 symmetry-based diol isostere)
SIV PR (MAC251-32H isolate)	1sip	hiv2bcl	Birkbeck College, Laboratory of Molecular Biology, London	*******	1994	N/A
HIV-1 PR (BH10 isolate) with penicillin - derived inhibitor GR137615	1htg	hiv3glx	Glaxo Group Research Limited	*******	1994	GR137615 (penicillin-derived inhibitor)
HIV-1 PR (LAI isolate) with inhibitor A76928	1hvc	hiv13nci	SAIC, NCI Frederick	*******	1994	A76928 (C2 symmetry-based diol isostere (S,S))
HIV-2 PR (ROD isolate) with inhibitor BILA 1906 containing hydroxyethylamine dipeptide izostere	1ida	hiv2bip	Boehringer Ingelheim Pharmaceuticalss	*******	1994	BILA 1906 (hydroxyethylamine isostere)
HIV-2 PR (ROD isolate) with inhibitor BILA 2450 containing hydroxyethylamine dipeptide izostere	1idb	hiv3bip	Boehringer Ingelheim Pharmaceuticalss	*******	1994	BILA 2450 (hydroxyethylamine isostere)
HIV-1 PR (BH5 isolate) with nonpeptide cyclic ureas as inhibitor XK263	1hvr	hiv1dpm	DuPont Merck Pharmaceuticals Company	*******	1994	XK263 (nonpeptidic ureas inhibitor)
HIV-2 PR (ROD isolate) mutant (K57L) with unidentified peptide fragment in active site	2hpe	hiv3ulk	Upjohn Company, Kalamazoo	*******	1994	N/A
HIV-2 PR (ROD isolate) mutant (K57L) with unidentified peptide fragment in active site	2hpf	hiv4ulk	Upjohn Company, Kalamazoo	*******	1994	N/A
HIV-1 PR (BH10 isolate) with inhibitor SB203238	1hbv	hiv8skb	SmithKline Beecham Pharmaceuticalss	*******	1995	SB203238 (reduced amide isostere)
HIV-1 PR (BRU isolate) with inhibitor CGP 53820	1hih	hiv1cgp	Ciba-Geigy Pharmaceuticals Ltd.	*******	1995	CGP53820 (hydroxyethylene isostere)
HIV-2 PR (ROD isolate) with inhibitor CGP 53820	1hii	hiv2cgp	Ciba-Geigy Pharmaceuticals Ltd.	*******	1995	CGP52820 (hydroxyethylene isostere)
HIV-1 PR (BRU isolate) with inhibitor VX-478,Amprenavir	1hpv	hiv1vpi	Vertex Pharmaceuticalss Incorporated	*******	1995	VX-478;141W94; Amprenavir; Agenerase® (hydroxyethylene isostere,amino sulfonamide inhibitor)
HIV-1 PR (BH5 isolate) V82A mutant with inhibitor A77003	1hvs	hiv14nci	SAIC, NCI Frederick	*******	1995	A77003 (C2 symmetry-based diol isostere (R,S))
HIV-1 PR (BRU isolate) with allophenylnorstatine inhibitor KNI - 272	1hpx	hiv15nci	SAIC, NCI Frederick	*******	1995	KNI-272 (allophenylnorstatine analog)
HIV-1 PR (ARV2/SF2 isolate) with cyclic peptide inhibitor	1cpi	hiv1uba	University of Queensland, Australia	*******	1995	(cyclic peptidomimetic inhibitor)
HIV-1 PR (BH5 isolate) complex with inhibitor U095438	1upj	hiv5ulk	Upjohn Company, Kalamazoo	*******	1995	U095438 (carboxamide-containing 4- hydroxycoumarin inhibitor)
HIV-1 PR (BH5 isolate) complex with inhibitor U100313	2upj	hiv6ulk	Upjohn Company, Kalamazoo	*******	1995	U100313 (4-hydroxy-2-pyrones inhibitor)
HIV-2 PR (isolate unknown) mutant (K57L) with inhibitor U096333	3upj	hiv7ulk	Upjohn Company, Kalamazoo	*******	1995	U096333 (carboxamide-containing 4-hydroxycoumarin inhibitor)
HIV-2 PR (isolate unknown) mutant (K57L) with inhibitor U097410	4upj	hiv8ulk	Upjohn Company, Kalamazoo	*******	1995	U096333 (carboxamide-containing 4-hydroxycoumarin inhibitor)
HIV-1 PR (unknown isolate) with a difluoroketone containing inhibitor A79285	1dif	hiv16nci	SAIC, NCI Frederick	*******	1996	A79285 (difluoroketone isostere)
HIV-1 PR (HXB2 isolate) with DMP323, a novel cyclic urea - type inhibitor (mutation C95A)	1bve	hiv1nid	NIDR Bethesda,MD	*******	1996	DMP323 (urea-type inhibitor)
HIV-1 PR (HXB2 isolate) with DMP323, a novel cyclic urea - type inhibitor (mutation C95A)	1bvg	hiv2nid	NIDR Bethesda,MD	*******	1996	DMP323 (urea-type inhibitor)
HIV-1 PR (PV22 isolate) mutant (V82D) with U89360E, a peptidic inhibitor	1gnm	hiv1uoc	University of Oklahoma	*******	1996	U89360E (peptidic inhibitor)
HIV-1 PR (PV22 isolate) mutant (V82N) with U89360E, a peptidic inhibitor	1gnn	hiv2uoc	University of Oklahoma	*******	1996	U89360E (peptidic inhibitor)
HIV-1 PR (PV22 isolate) wild type with U89360E, a peptidic inhibitor	1gno	hiv3uoc	University of Oklahoma	*******	1996	U89360E (peptidic inhibitor)
HIV-1 PR (ARV2/SF2 isolate) (mutant) complexed with a cyclic Phe - Ile - Val peptidomimetic inhibitor	1mtr	hiv2uba	University of Queensland, Australia	*******	1996	Phe-Ile-Val (cyclic peptidomimetic inhibitor)
HIV-1 PR (Z2 isolate) dimer complex with inhibitor A-98881	1pro	hiv2abb	Abbott Laboratories Dept. of CAMD	*******	1996	A-98881 (urea-type inhibitor)
HIV-1 PR (HXB-3 isolate) complex with inhibitor RO 31-8959 [INVIRASE (saquinavir)]	1hxb	hiv1hlr	Hoffmann-La Roche	*******	1996	RO 31-8959, saquinavir;Invirase® ; Fortovase®; hydroxyethylamine isostere
HIV-1 PR (HXB-2 isolate) complex with inhibitor BMS-182193	1odw	hiv17nci	ABL-BRP, NCI Frederick	*******	1996	BMS-182193 aminodiol isostere
HIV-1 PR (HXB-2 isolate) mutant A71T, V82A with inhibitor BMS-182193	1odx	hiv18nci	ABL-BRP, NCI Frederick	*******	1996	BMS-182193 aminodiol isostere
SIV PR (MAC 251 isolate) with inhibitor SB203386	1tcw	hiv9skb	SmithKline Beecham Pharmaceuticalss	*******	1996	SB203386
HIV-1 PR (SF-2 strain) mutant Q7K with peptide product	1ytg	hiv2ucs	University of California San Francisco	*******	1996	peptide product
HIV-1 PR (SF-2 strain) mutant Q7K with peptide product	1yth	hiv3ucs	University of California San Francisco	*******	1996	peptide product
SIV PR (MAC 239 isolate) mutant S4H with peptide product	1yti	hiv4ucs	University of California San Francisco	*******	1996	peptide product
SIV PR (MAC 239 isolate) mutant S4H with peptide product	1ytj	hiv5ucs	University of California a San Francisco	*******	1996	peptide product
HIV-1 PR (BH102 isolate) with inhibitor DMP450	1dmp	hiv14dpm	DuPont Merck Pharmaceuticals Company	*******	1996	DMP 450
HIV-1 PR with inhibitor SB203386	1tcx	hiv13skb	SmithKline Beecham Pharmaceuticalss	*******	1996	SB203386
HIV-1 PR (BH10 isolate) with cyclic sulfoamide inhibitor AHA006	1ajv	hiv1upp	Uppsala University, Sweden	*******	1997	AHA006 cyclic sulfoamide
HIV-1 PR (BH10 isolate) with cyclic sulfoamide inhibitor AHA001	1ajx	hiv2upp	Uppsala University, Sweden	*******	1997	AHA001 cyclic urea inhibitor
HIV-1 PR (SF1 isolate) with a nonpeptide inhibitor THK	1aid	hiv6ucd	University of California San Francisco	*******	1997	THK nonpeptidic inhibitor
HIV-1 PR with inhibitor A-84538,ABT-538 [NORVIR (Ritonavir)]	1hxw	hiv3abb	Abbott Laboratories	*******	1997	A-84538,ABT-538
HIV-2 PR with inhibitor containing a novel (hydroxyethyl)amide isostere	1jld	hiv6bip	Boehringer Ingelheim Pharmaceuticalss	*******	1997	BILA-N/A
HIV-1 PR (BH102 strain) I84V mutations with inhibitor DMP450	1mer	hiv6dpm	DuPont Merck Pharmaceuticals Company	*******	1997	DMP-450
HIV-1 PR (BH102 strain) I84V mutations with inhibitor DMP323	1mes	hiv7dpm	DuPont Merck Pharmaceuticals Company	*******	1997	DMP-323
HIV-1 PR (BH102 strain) V82F mutations with inhibitor DMP323	1met	hiv8dpm	DuPont Merck Pharmaceuticals Company	*******	1997	DMP-323
HIV-1 PR (BH102 strain) V82F,I84V mutations with inhibitor DMP323	1meu	hiv9dpm	DuPont Merck Pharmaceuticals Company	*******	1997	DMP-323
HIV-1 PR (BH102 strain) with cyclic urea amide inhibitor	1qbr	hiv15dpm	DuPont Merck Pharmaceuticals Company	*******	1997	cyclic urea amide inhibitor
HIV-1 PR (BH102 strain) with cyclic urea amide inhibitor	1qbs	hiv16dpm	DuPont Merck Pharmaceuticals Company	*******	1997	cyclic urea amide inhibitor
HIV-1 PR (BH102 strain) with cyclic urea amide inhibitor	1qbt	hiv17dpm	DuPont Merck Pharmaceuticals Company	*******	1997	cyclic urea amide inhibitor
HIV-1 PR (BH102 strain) with cyclic urea amide inhibitor	1qbu	hiv18dpm	DuPont Merck Pharmaceuticals Company	*******	1997	cyclic urea amide inhibitor
HIV-1 PR (SF2 strain) with a nonpeptide inhibitor	2aid	hiv7ucs	University of California San Francisco	*******	1997	nonpeptide inhibitor
HIV-1 PR (SF strain) Q7K mutant with an aminimide peptide isostere inhibitor	3aid	hiv8ucs	University of California San Francisco	*******	1997	aminimide peptide isostere inhibitor
HIV-1 PR (isolate unknown) complexed with AG-1343[Viracept (Nelfinavir)]	1ohr	hiv19aug	Agouron Pharmaceuticals	*******	1997	Nelfinavir Mesylate
HIV-1 PR (HXB2 isolate) with a hydrophylic tripeptide inhibitor Glu-Asp-Leu	1a30	hiv1nih	National Institute of Health Bethesda	*******	1998	GLU-ASP-LEU hydrophylic tripeptide inhibitorderived from the transframe region of Gag-Pol
HIV-1 PR with inhibitor SDZ283-910	1a8g	hiv1sag	Sandoz Research Institute Vienna, Austria	*******	1998	SDZ283-910
HIV-1 PR G48H mutant with inhibitor U-89360E	1a9m	hiv4uoc	University of Oklahoma	*******	1998	U-89360E
SIV PR unliganded protease in an "open" conformation	1az5	hiv6ucs	University of California San Francisco	*******	1998	N/A
HIV-1 PR (K7Q, I33L,I63L mutant) with an analog of the conserved Ca-P2 substrate	1a8k	hiv1tju	Thomas Jefferson University Philadelphia	*******	1998	N/A
HIV-1 PR T31S, V32I, L33V, E34A, E35G, M36I, S37E mutations with inhibitor SB203386	1bdl	hiv10skb	SmithKline Beecham Pharmaceuticalss	*******	1998	SB203386
HIV-1 PR T31S, V32I, L33V, E34A, E35G, M36I, S37E, I47V,V82I mutations with inhibitor SB203386	1bdq	hiv11skb	SmithKline Beecham Pharmaceuticalss	*******	1998	SB203386
HIV-1 PR T31S, L33V, E34T, E35G, M36I, S37E mutations with inhibitor SB203386	1bdr	hiv12skb	SmithKline Beecham Pharmaceuticalss	*******	1998	SB203386
HIV-1 PR (BH102 strain) I82F, C95A mutations with inhibitor SD146	1bv7	hiv10dpm	DuPont Merck Pharmaceuticals Company	*******	1998	SD146
HIV-1 PRI (BH102 strain) I84V,C95A mutations with inhibitor XV638 (cyclic urea inhibitor)	1bv9	hiv11dpm	DuPont Merck Pharmaceuticals Company	*******	1998	XV638
HIV-1 PR V82F, I84V mutations with inhibitor XV638 (cyclic urea inhibitor)	1bwa	hiv12dpm	DuPont Merck Pharmaceuticals Company	*******	1998	XV638
HIV-1 PR (BH102 strain) V82F, I84V mutations with inhibitor SD146	1bwb	hiv13dpm	DuPont Merck Pharmaceuticals Company	*******	1998	SD146
HIV-1 PR A28S mutant, with inhibitor U89360E	1axa	hiv5uoc	University of Oklahoma	*******	1999	U89360E
HIV-1 PR (BH102 strain) with inhibitor Q8261	1hvh	hiv19dpm	DuPont Merck Pharmaceuticals Company	*******	1999	Q8261, Nonpeptide Cyclic Cyanoguanidines
HIV-1 PR (BH102 strain) with inhibitor XK216	1hwr	hiv20dpm	DuPont Merck Pharmaceuticals Company	*******	1999	XK216
HIV-1 PR (HXB2 isolate) with inhibitor LP-130	1ody	hiv20nci	ABL-BRP, NCI Frederick	*******	1999	LP-130
HIV-1 PR With The Inhibitor HOE/BAY 793	1vij	hiv1imb	IMB Jena	*******	1999	HOE/BAY 793
HIV-1 PR With The Inhibitor HOE/BAY 793	1vik	hiv2imb	IMB Jena	*******	1999	HOE/BAY 793
HIV-1 PR (NY5 isolate) with inhibitor L-738,317	2bpv	hiv12msd	Merck Sharp and Dohme Res. Lab	*******	1999	L-738,317
HIV-1 PR (NY5 isolate) with inhibitor L-738,317	2bpw	hiv13msd	Merck Sharp and Dohme Res. Lab	*******	1999	L-738,317
HIV-1 PR (NY5 isolate) with inhibitor L-735,524	2bpx	hiv14msd	Merck Sharp and Dohme Res. Lab	*******	1999	L-735,524,MK-639,Indinavir,Crixivan
HIV-1 PR (NY5 isolate) with inhibitor L-739,622	2bpy	hiv15msd	Merck Sharp and Dohme Res. Lab	*******	1999	L-739,622
HIV-1 PR (NY5 isolate) with inhibitor L-739,622	2bpz	hiv16msd	Merck Sharp and Dohme Res. Lab	*******	1999	L-739,622
HIV-1 PR (synthetic construct SF isolate) with macrocyclic peptidomimetic inhibitor	1d4k	hiv3uba	University of Queensland, Australia	*******	1999	PI9
HIV-1 PR (synthetic construct SF isolate) mutant with macrocyclic peptidomimetic inhibitor	1d4l	hiv4uba	University of Queensland, Australia	*******	1999	PI9
HIV-1 PR V82F/I84V Double Mutant/Tipranavir Complex	1d4s	hiv23ulk	Upjohn Company, Kalamazoo	*******	1999	U-140690; PNU-140690;Tipranavir
HIV-1 PR Q7K, L33I, L63I Triple Mutant/Tipranavir Complex	1d4y	hiv24ulk	Upjohn Company, Kalamazoo	*******	1999	U-140690; PNU-140690;Tipranavir
HIV-1 PR Q7K, L33I, L63I, C67A, L90M, C95A mutant , analogue of CA-P2 processing site	1dw6	hiv3tju	Thomas Jefferson University Philadelphia	*******	2000	CA-p2 analog inhibitor
HIV-1 PR Q7K, L33I, L63I, C67A, L90M, C95A mutant , analogue of CA-P2 processing site	1ebk	hiv4tju	Thomas Jefferson University Philadelphia	*******	2000	CA-p2 analog inhibitor
HIV-1 PR with saquinavir	1fb7	hiv6uoc	University of Oklahoma	*******	2000	saquinavir
HIV-1 PR with inhibitor Aha024 -Symmetric and Nonsymmetric Cyclic Sulfamide HIV-1 Protease Inhibitors	1g35	hiv5upp	Uppsala University, Sweden	*******	2000	Aha024
HIV-1 PR Crystal Structure Of Tethered Hiv-1 Protease	1g6l	hiv1bar	Bhabha Atomic Research Centre, Trombay, Mumbai, India	*******	2000	N/A
HIV-1 PR (NY5 isolate) with L-756,423 inhibitor; resistant mutant L10V,K20M,L24I,S37D,M46I,I54V,L63P,A71V,V82T	1c70	hiv1mrl	Merck Research Laboratories, West Point, PA, USA	*******	2000	L-756,423
HIV-1 PR (NY5 isolate) with L-756,423 inhibitor; resistant mutant L10V,K20M,L24I,S37D,M46I,I54V,L63P,A71V,V82T	1c6z	hiv2mrl	Merck Research Laboratories, West Point, PA, USA	*******	2000	SAQUINAVIR, Ro 31-8959;Invirase® ; Fortovase®;
HIV-1 PR (NY5 isolate) with L-756,423 inhibitor; resistant mutant L10V,K20M,L24I,S37D,M46I,I54V,L63P,A71V,V82T	1c6y	hiv3mrl	Merck Research Laboratories, West Point, PA, USA	*******	2000	L-735,524,MK-639,Indinavir,Crixivan
HIV-1 PR (NY5 isolate) with L-756,423 inhibitor; resistant mutant L10V,K20M,L24I,S37D,M46I,I54V,L63P,A71V,V82T	1c6x	hiv4mrl	Merck Research Laboratories, West Point, PA, USA	*******	2000	L-739,622
HIV-1 PR with macrocyclic peptidomimetic inhibitor 1 (ABA67,95C)	1d4k	hiv5uba	University of Queensland, Australia	*******	2000	macrocyclic peptidomimetic inhibitor 1
HIV-1 PR with macrocyclic peptidomimetic inhibitor 1 (Q7K,L33I,C67ABA,C95ABA)	1d4l	hiv6uba	University of Queensland, Australia	*******	2000	macrocyclic peptidomimetic inhibitor 1
HIV-1 PR with macrocyclic peptidomimetic inhibitor 1 (C67ABA,C95ABA)	1b6j	hiv7uba	University of Queensland, Australia	*******	2000	macrocyclic peptidomimetic inhibitor 1
HIV-1 PR with macrocyclic peptidomimetic inhibitor 2 (Q7K,L33I,C67ABA,C95ABA)	1b6o	hiv8uba	University of Queensland, Australia	*******	2000	macrocyclic peptidomimetic inhibitor 2
HIV-1 PR (Arv2/Sf2 Isolate) with macrocyclic peptidomimetic inhibitor 6, (Q7K,L33I,C67ABA,C95ABA)	1b6m	hiv9uba	University of Queensland, Australia	*******	2000	macrocyclic peptidomimetic inhibitor 6
HIV-1 PR with macrocyclic peptidomimetic inhibitor 4, (Q7K,L33I,C67ABA,C95ABA)	1b6l	hiv10uba	University of Queensland, Australia	*******	2000	macrocyclic peptidomimetic inhibitor 4
HIV-1 PR with macrocyclic peptidomimetic inhibitor 3, (Q7K,L33I,C67ABA,C95ABA)	1b6n	hi11uba	University of Queensland, Australia	*******	2000	macrocyclic peptidomimetic inhibitor 3
HIV-1 PR with macrocyclic peptidomimetic inhibitor 5, (Q7K,L33I,C67ABA,C95ABA)	1b6k	hiv12uba	University of Queensland, Australia	*******	2000	macrocyclic peptidomimetic inhibitor 5
HIV-1 PR with macrocyclic peptidomimetic inhibitor 7, (Q7K,L33I,C67ABA,C95ABA)	1b6p	hiv113uba	University of Queensland, Australia	*******	2000	macrocyclic peptidomimetic inhibitor 7
HIV-1 PR With Cyclic Sulfamide Inhibitor, Aha047	1g2k	hiv5upp	Uppsala Biomedical Centre, Uppsala University, Sweden	*******	2001	Aha047
HIV-1 PR With A Peptidomimetic Inhibitor	1fqx	hiv1umc	Institute of Macromolecular Chemistry,AS CR, Prague, Czech republic	*******	2001	Boc-Phe-[(S)-Ch(Oh)Ch2Nh] -Phe-Glu-Phe-Nh2
HIV-1 PR with peptide inhibitor, Q7K, L33I, L63I, C67A,D30N, K45I, N88D,L90M mutations	1fgc	hiv1gsu	Georgia State University, Atlanta, Georgia,USA	*******	2001	Peptide Inhibitor (Ace)Ti(Nle)(Nle)Qr
HIV-1 PR with peptide inhibitor, Q7K, L33I, L63I, C67A,D30N, K45I, N88D,L90M mutations	1fg8	hiv2gsu	Georgia State University, Atlanta, Georgia,USA	*******	2001	Peptide Inhibitor Rv(Dcl)Fea(Nle);
HIV-1 PR with peptide inhibitor, Q7K, L33I, L63I, C67A,D30N, K45I, N88D,L90M mutations	1fg6	hiv3gsu	Georgia State University, Atlanta, Georgia,USA	*******	2001	Peptide Inhibitor (Ace)Ti(Nle)(Nle)Qr
HIV-1 PR with peptide inhibitor, Q7K, L33I, L63I, C67A,D30N, K45I, N88D,L90M mutations	1ffi	hiv4gsu	Georgia State University, Atlanta, Georgia,USA	*******	2001	Peptide Inhibitor (Ace)Ti(Nle)(Nle)Qr
HIV-1 PR with peptide inhibitor, Q7K, L33I, L63I, C67A,D30N, K45I, N88D,L90M mutations	1fff	hiv5gsu	Georgia State University, Atlanta, Georgia,USA	*******	2001	Peptide Inhibitor Rv(Dcl)Fea(Nle);
HIV-1 PR with peptide inhibitor, Q7K, L33I, L63I, C67A,D30N, K45I, N88D,L90M mutations	1ff0	hiv6gsu	Georgia State University, Atlanta, Georgia,USA	*******	2001	Peptide Inhibitor (Ace)Ti(Nle)(Nle)Qr;
HIV-1 PR with peptide inhibitor, Q7K, L33I, L63I, C67A,D30N, K45I, N88D,L90M mutations	1fej	hiv7gsu	Georgia State University, Atlanta, Georgia,USA	*******	2001	Peptide Inhibitor (Ace)Ti(Nle)(Nle)Qr
HIV-1 PR (L63P, V82T, I84V) mutant with Indinavir analog	1k6c	hiv1uma	University of Massachusetts Medical School, Worcester,USA	*******	2002	INDINAVIR
HIV-1 PR (L63P, V82T, I84V) mutant with Indinavir analog	1k6p	hiv2uma	University of Massachusetts Medical School, Worcester,USA	*******	2002	Indinavir analog
HIV-1 PR (L63P, V82T, I84V) mutant with Indinavir analog	1k6t	hiv3uma	University of Massachusetts Medical School, Worcester,USA	*******	2002	Indinavir analog
HIV-1 PR (L63P, V82T, I84V) mutant with Indinavir analog	1k6v	hiv4uma	University of Massachusetts Medical School, Worcester,USA	*******	2002	Indinavir analog
UNOFFICIAL RELEASES The year of release of the structure does not necessarily correspond to the year in which it was solved
System	PDB File	HIVdb File	Company or Laboratory		Year	Inhibitor (Type)
HIV-1 PR (isolate unknown) with inhibitor RO31-8558	N/A	hiv2hlr	Hoffmann-La Roche	**	1991	RO31-8558 hydroxyethylamine isostere
HIV-1 PR (isolate unknown) with inhibitor AG1001	N/A	hiv1aug	Agouron Pharmaceuticals	**	1991	AG1001
HIV-1 PR (isolate unknown) with inhibitor AG1002	N/A	hiv2aug	Agouron Pharmaceuticals	**	1991	AG1002
HIV-1 PR (isolate unknown) with inhibitor AG1004	N/A	hiv3aug	Agouron Pharmaceuticals	**	1991	AG1004
HIV-1 PR (isolate unknown) with inhibitor LILLY765	N/A	hiv1lll	Lilly Pharmaceuticals	**	1991	LILLY765
HIV-1 PR (isolate unknown) with inhibitor I-BMS-01	N/A	hiv1bms	Bristol-Myers Squibb	**	1993	I-BMS-01
HIV-1 PR (isolate unknown) with inhibitor I-BMS-02	N/A	hiv2bms	Bristol-Myers Squibb	**	1993	I-BMS-02
HIV-2 PR (isolate unknown) with inhibitor BILA-2011	N/A	hiv4bip	Boehringer Ingelheim Pharmaceuticalss	**	1995	BILA-2011
HIV-2 PR (isolate unknown) with inhibitor BILA-1780	N/A	hiv5bip	Boehringer Ingelheim Pharmaceuticalss	**	1995	BILA-1780
HIV-1 PR mutant C95A (BH102 isolate) with inhibitor DMP323	N/A	hiv2dpm	DuPont Merck Pharmaceuticals Company	**	1996	DMP323 urea based inhibitor
HIV-1 PR mutant C95A (BH102 isolate) with inhibitor Q8467	N/A	hiv3dpm	DuPont Merck Pharmaceuticals Company	**	1997	Q8467 cyclic urea amid inhibitor
HIV-1 PR mutant C95A (BH102 isolate) with inhibitor XV638	N/A	hiv4dpm	DuPont Merck Pharmaceuticals Company	**	1997	XV638 cyclic urea amid inhibitor
HIV-1 PR mutant C95A (BH102 isolate) with inhibitor SD146	N/A	hiv5dpm	DuPont Merck Pharmaceuticals Company	**	1997	SD146 cyclic urea amid inhibitor
HIV-1 PR (isolate unknown) with inhibitor	N/A	hiv4glx	Glaxo Group Research Limited	**	1991	GR-XXXX
HIV-1 PR (ROD isolate) with inhibitor L-689,502	N/A	hiv7msd	Merck Sharp and Dohme Res. Lab	**	1992	L-689,502
HIV-1 PR (BH-10 isolate) with inhibitor MDL 104,168	N/A	hiv1mmd	MMDRI, France	**	1993	MDL 104,168 difluorostatone inhibitor
HIV-1 PR (BH-10 isolate) with inhibitor MDL 73,669	N/A	hiv2mmd	MMDRI, France	**	1993	MDL 73,669 difluorostatone inhibitor
HIV-1 PR (BH-10 isolate) with inhibitor MDL 73,730	N/A	hiv3mmd	MMDRI, France	**	1993	MDL 73,730 difluorostatone inhibitor
HIV-1 PR (BH-10 isolate) with inhibitor MDL 73,881	N/A	hiv4mmd	MMDRI, France	**	1993	MDL 73,881 difluorostatone inhibitor
HIV-1 PR (BH-10 isolate) with inhibitor MDL 73,915	N/A	hiv5mmd	MMDRI, France	**	1993	MDL 73,915 difluorostatone inhibitor
HIV-1 PR (BH-10 isolate) with inhibitor MDL 74,538	N/A	hiv6mmd	MMDRI, France	**	1993	MDL 74,538 difluorostatone inhibitor
HIV-1 PR (BH-10 isolate) with inhibitor MDL 75,635	N/A	hiv7mmd	MMDRI, France	**	1993	MDL 75,635 difluorostatone inhibitor
HIV-1 PR (BH-10 isolate) with inhibitor MDL 75,305	N/A	hiv8mmd	MMDRI, France	**	1993	MDL 75,305 difluorostatone inhibitor
HIV-1 PR (BH-10 isolate) with inhibitor AHA004	N/A	hiv3upp	Uppsala University, Sweden	**	1997	AHA004 cyclic urea inhibitor
HIV-1 PR (BH-10 isolate) with inhibitor AHA009	N/A	hiv4upp	Uppsala University, Sweden	**	1997	AHA009 sulfoamide inhibitor
HIV-2 PR (isolate unknown) K57L mutant with inhibitor U099283	5upj	hiv9ulk	Upjohn Company, Kalamazoo	**	1997	U099283
HIV-2 PR (isolate unknown) K57L mutant with inhibitor U099294	6upj	hiv10ulk	Upjohn Company, Kalamazoo	*******	1997	U099294
HIV-1 PR (BH5 isolate) with inhibitor U101935	7upj	hiv11ulk	Upjohn Company, Kalamazoo	*******	1997	U101935
HIV-1 PR (triple mutant Q7K/L33I/L63I) with inhibitor U103265	1hpo	hiv12ulk	Upjohn Company, Kalamazoo	*******	1997	U103265
HIV-1 PR (isolate unknown) with inhibitor L-738816	N/A	hiv8msd	Merck Sharp and Dohme Res. Lab	**	1997	L-738,816
HIV-1 PR (isolate unknown) with inhibitor L-739622	N/A	hiv9msd	Merck Sharp and Dohme Res. Lab	**	1997	L-739,622
HIV-1 PR (isolate unknown) with inhibitor L-771786	N/A	hiv10msd	Merck Sharp and Dohme Res. Lab	**	1997	L-771,786
HIV-1 PR (isolate unknown) with inhibitor AP248	N/A	hiv11msd	Merck Sharp and Dohme Res.Lab	**	1997	AP248
HIV-1 PR (isolate unknown) with cyclopropan peptidomimetic inhibitor	N/A	hiv19nci	SAIC, NCI Frederick	**	1998	cyclopropan peptidomimetic inhibitor
HIV-2 PR K57L mutant with inhibitor U97829	N/A	hiv13ulk	Upjohn Company, Kalamazoo	**	1996	U97829
HIV-2 PR with inhibitor U98807	N/A	hiv14ulk	Upjohn Company, Kalamazoo	**	1993	U98807
HIV-2 PR K57L mutant with inhibitor U098718	N/A	hiv15ulk	Upjohn Company, Kalamazoo	**	1996	U098718
HIV-2 PR K57L mutant with inhibitor U098718-A	N/A	hiv16ulk	Upjohn Company, Kalamazoo	**	1996	U098718-A
HIV-2 PR K57L mutant with inhibitor U103774	N/A	hiv17ulk	Upjohn Company, Kalamazoo	**	1998	U103774
HIV-1 PR with inhibitor U104661	N/A	hiv18ulk	Upjohn Company, Kalamazoo	**	1998	U104661
HIV-1 PR with inhibitor U101935	N/A	hiv19ulk	Upjohn Company, Kalamazoo	**	1998	U101935
HIV-1 PR with inhibitor U101935	N/A	hiv20ulk	Upjohn Company, Kalamazoo	**	1998	U101935
HIV-1 PR (triple mutant Q7K/L33I/L63I) with inhibitor U103695	N/A	hiv21ulk	Upjohn Company, Kalamazoo	**	1998	U103695
HIV-1 PR (triple mutant Q7K/L33I/L63I) with inhibitor U102812	N/A	hiv22ulk	Upjohn Company, Kalamazoo	**	1998	U102812
HIV-1 PR (isolate unknown) with inhibitor AG1146	N/A	hiv4aug	Agouron Pharmaceuticals	**	1999	AG1146
HIV-1 PR (isolate unknown) with inhibitor AG1174	N/A	hiv5aug	Agouron Pharmaceuticals	**	1999	AG1174
HIV-1 PR (isolate unknown) with inhibitor AG1204	N/A	hiv6aug	Agouron Pharmaceuticals	**	1999	AG1204
HIV-1 PR (isolate unknown) with inhibitor AG1216	N/A	hiv7aug	Agouron Pharmaceuticals	**	1999	AG1216
HIV-1 PR (isolate unknown) with inhibitor AG1220	N/A	hiv8aug	Agouron Pharmaceuticals	**	1999	AG1220
HIV-1 PR (isolate unknown) with inhibitor AG1221	N/A	hiv9aug	Agouron Pharmaceuticals	**	1999	AG1221
HIV-1 PR (isolate unknown) with inhibitor AG1225	N/A	hiv10aug	Agouron Pharmaceuticals	**	1999	AG1225
HIV-1 PR (isolate unknown) with inhibitor AG1232	N/A	hiv11aug	Agouron Pharmaceuticals	**	1999	AG1232
HIV-1 PR (isolate unknown) with inhibitor AG1235	N/A	hiv12aug	Agouron Pharmaceuticals	**	1999	AG1235
HIV-1 PR (isolate unknown) with inhibitor AG1240	N/A	hiv13aug	Agouron Pharmaceuticals	**	1999	AG1240
HIV-1 PR (isolate unknown) with inhibitor AG1254	N/A	hiv14aug	Agouron Pharmaceuticals	**	1999	AG1254
HIV-1 PR (isolate unknown) with inhibitor AG1256	N/A	hiv15aug	Agouron Pharmaceuticals	**	1999	AG1256
HIV-1 PR (isolate unknown) with inhibitor AG1274	N/A	hiv16aug	Agouron Pharmaceuticals	**	1999	AG1274
HIV-1 PR (isolate unknown) with inhibitor AG1276	N/A	hiv17aug	Agouron Pharmaceuticals	**	1999	AG1276
HIV-1 PR (isolate unknown) with inhibitor AG1284	N/A	hiv18aug	Agouron Pharmaceuticals	**	1999	AG1284
UNOFFICIAL RELEASES - NOT VALIDATED BY AUTHORS The year of release of the structure does not necessarily correspond to the year in which it was solved
HIV-1 PR (isolate unknown) with inhibitor P 747	N/A	hiv21nci	SAIC, NCI Frederick	*	2002	p747
HIV-1 PR (isolate unknown) with inhibitor RO8588	N/A	hiv22nci	SAIC, NCI Frederick	*	2002	RO 8588
HIV-1 PR (isolate unknown) with inhibitor ROCHE 1	N/A	hiv23nci	SAIC, NCI Frederick	*	2002	ROCHE I1
HIV-1 PR (isolate unknown) with inhibitor RR-DIOL	N/A	hiv24nci	SAIC, NCI Frederick	*	2002	RR-DIOL
HIV-1 PR (isolate unknown) with inhibitor U75875	N/A	hiv25nci	SAIC, NCI Frederick	*	2002	U75875
HIV-1 PR (isolate unknown) with inhibitor U85548E	N/A	hiv26nci	SAIC, NCI Frederick	*	2002	U 85548E
HIV-1 PR (isolate unknown) with inhibitor UPJ2	N/A	hiv27nci	SAIC, NCI Frederick	*	2002	UPJ2
HIV-1 PR (isolate unknown) with inhibitor P204144	N/A	hiv28nci	SAIC, NCI Frederick	*	2002	P 204144
HIV-1 PR (isolate unknown) with inhibitor A74704	N/A	hiv29nci	SAIC, NCI Frederick	*	2002	A74704
HIV-1 PR (isolate unknown) with inhibitor A76215	N/A	hiv30nci	SAIC, NCI Frederick	*	2002	A 76215
HIV-1 PR (isolate unknown) with inhibitor A77003	N/A	hiv31nci	SAIC, NCI Frederick	*	2002	A 77003
HIV-1 PR (isolate unknown) V32I, V82I mutant, with inhibitor A77003	N/A	hiv32nci	SAIC, NCI Frederick	*	2002	A 77003
HIV-1 PR (isolate unknown) V82I, I84V mutant, with inhibitor A77003	N/A	hiv33nci	SAIC, NCI Frederick	*	2002	A 77003
HIV-1 PR (isolate unknown) with inhibitor A79600	N/A	hiv34nci	SAIC, NCI Frederick	*	2002	A 79600
HIV-1 PR (isolate unknown) with inhibitor A82108	N/A	hiv35nci	SAIC, NCI Frederick	*	2002	A 82108
HIV-1 PR (isolate unknown) with inhibitor A84538	N/A	hiv36nci	SAIC, NCI Frederick	*	2002	A 84538
HIV-1 PR (isolate unknown) I84V mutant with inhibitor A84538	N/A	hiv37nci	SAIC, NCI Frederick	*	2002	A 84538
HIV-1 PR (isolate unknown) with inhibitor ABT2	N/A	hiv38nci	SAIC, NCI Frederick	*	2002	ABT 2
HIV-1 PR (isolate unknown) with inhibitor ABT538	N/A	hiv39nci	SAIC, NCI Frederick	*	2002	ABT 538
HIV-1 PR (isolate unknown) V82A mutant with inhibitor ABT538	N/A	hiv40nci	SAIC, NCI Frederick	*	2002	ABT 538
HIV-1 PR (isolate unknown) with inhibitor AN78	N/A	hiv41nci	SAIC, NCI Frederick	*	2002	AN 78
HIV-1 PR (isolate unknown) with inhibitor BILA01	N/A	hiv42nci	SAIC, NCI Frederick	*	2002	BILA 01
HIV-1 PR (isolate unknown) V42I mutant with inhibitor BILA01	N/A	hiv43nci	SAIC, NCI Frederick	*	2002	BILA 01
HIV-1 PR (isolate unknown) with inhibitor CK11	N/A	hiv44nci	SAIC, NCI Frederick	*	2002	CK11
HIV-1 PR (isolate unknown) with inhibitor DIOL 10	N/A	hiv45nci	SAIC, NCI Frederick	*	2002	DIOL 10
HIV-1 PR (isolate unknown) with inhibitor R 31-8624	N/A	hiv46nci	SAIC, NCI Frederick	*	2002	R 31-8624
HIV-1 PR (isolate unknown) with inhibitor DIOL 38	N/A	hiv47nci	SAIC, NCI Frederick	*	2002	DIOL 38
HIV-1 PR (isolate unknown) with inhibitor DIOL 48	N/A	hiv48nci	SAIC, NCI Frederick	*	2002	DIOL 48
HIV-1 PR (isolate unknown) with inhibitor R 31-8875	N/A	hiv49nci	SAIC, NCI Frederick	*	2002	R 31-8875
HIV-1 PR (isolate unknown) with inhibitor DN 14	N/A	hiv50nci	SAIC, NCI Frederick	*	2002	DN 14
HIV-1 PR (isolate unknown) with inhibitor DN 52	N/A	hiv51nci	SAIC, NCI Frederick	*	2002	DN 52
HIV-1 PR (isolate unknown) with inhibitor EPI-ROCHE	N/A	hiv52nci	SAIC, NCI Frederick	*	2002	EPI-ROCHE
HIV-1 PR (isolate unknown) with inhibitor GS 4145	N/A	hiv53nci	SAIC, NCI Frederick	*	2002	GS 4145
HIV-1 PR (isolate unknown) with inhibitor KNI_CYX	N/A	hiv54nci	SAIC, NCI Frederick	*	2002	KNI_CYX
HIV-1 PR (isolate unknown) with inhibitor KNI 241	N/A	hiv55nci	SAIC, NCI Frederick	*	2002	KNI 241
HIV-1 PR (isolate unknown) with inhibitor KNI 272	N/A	hiv56nci	SAIC, NCI Frederick	*	2002	KNI 272
HIV-1 PR (isolate unknown) V32I, K45I, F53I, A71V, I84V, L89M mutant with inhibitor KNI 272	N/A	hiv57nci	SAIC, NCI Frederick	*	2002	KNI 272
HIV-1 PR (isolate unknown) with inhibitor KNI 272_ASP	N/A	hiv58nci	SAIC, NCI Frederick	*	2002	KNI 272_ASP (N/A)
HIV-1 PR (isolate unknown) with inhibitor KNI 272_CYX_MOD	N/A	hiv59nci	SAIC, NCI Frederick	*	2002	KNI 272_CYX_MOD(N/A)
HIV-1 PR (isolate unknown) with inhibitor KNI 272_CYX_VAL	N/A	hiv60nci	SAIC, NCI Frederick	*	2002	KNI 272 CYX_VAL(N/A)
HIV-1 PR (isolate unknown) I84V mutant with inhibitor KNI 272	N/A	hiv61nci	SAIC, NCI Frederick	*	2002	KNI 272
HIV-1 PR (isolate unknown) L90M mutant with inhibitor KNI 272	N/A	hiv62nci	SAIC, NCI Frederick	*	2002	KNI 272
HIV-1 PR (isolate unknown) with inhibitor KNI 272M	N/A	hiv63nci	SAIC, NCI Frederick	*	2002	KNI 272M
HIV-1 PR (isolate unknown) with inhibitor KNI 272M	N/A	hiv64nci	SAIC, NCI Frederick	*	2002	KNI 272M
HIV-1 PR (isolate unknown) V82V mutant with inhibitor KNI 272	N/A	hiv65nci	SAIC, NCI Frederick	*	2002	KNI 272
HIV-1 PR (isolate unknown) V32I mutant with inhibitor KNI 327	N/A	hiv66nci	SAIC, NCI Frederick	*	2002	KNI 327
HIV-1 PR (isolate unknown) with inhibitor KOREA1	N/A	hiv67nci	SAIC, NCI Frederick	*	2002	KOREA1
HIV-1 PR (isolate unknown) with inhibitor LB71350	N/A	hiv68nci	SAIC, NCI Frederick	*	2002	LB71350
HIV-1 PR (isolate unknown) with inhibitor ND4	N/A	hiv69nci	SAIC, NCI Frederick	*	2002	ND 4
HIV-1 PR (isolate unknown) with inhibitor PD 150280	N/A	hiv70nci	SAIC, NCI Frederick	*	2002	PD 150280
HIV-1 PR (isolate unknown) with inhibitor PD 154617	N/A	hiv71nci	SAIC, NCI Frederick	*	2002	PD 154617
HIV-1 PR (isolate unknown) with inhibitor PD 154906	N/A	hiv72nci	SAIC, NCI Frederick	*	2002	PD 154906
HIV-1 PR (isolate unknown) with inhibitor PD 155339	N/A	hiv73nci	SAIC, NCI Frederick	*	2002	PD 155339
HIV-1 PR (isolate unknown) with inhibitor PD 164238	N/A	hiv74nci	SAIC, NCI Frederick	*	2002	PD 164283
HIV-1 PR (isolate unknown) with inhibitor PD 164409	N/A	hiv75nci	SAIC, NCI Frederick	*	2002	PD 164409
HIV-1 PR (isolate unknown) V82F, I84V mutant with inhibitor PD 173606	N/A	hiv76nci	SAIC, NCI Frederick	*	2002	PD 173606
HIV-1 PR (isolate unknown) with inhibitor PD 99560	N/A	hiv77nci	SAIC, NCI Frederick	*	2002	PD 99560
HIV-1 PR (isolate unknown) with inhibitor PD 173606	N/A	hiv78nci	SAIC, NCI Frederick	*	2002	PD 173606
HIV-1 PR (isolate unknown) G48V, L90M mutant with inhibitor RO 31-8959	N/A	hiv79nci	SAIC, NCI Frederick	*	2002	RO 31-8959
HIV-1 PR (isolate unknown) L90M mutant with inhibitor RO 31-8959	N/A	hiv80nci	SAIC, NCI Frederick	*	2002	RO 31-8959
HIV-1 PR (isolate unknown) with inhibitor RO 8588	N/A	hiv81nci	SAIC, NCI Frederick	*	2002	RO 8588
HIV-1 PR (isolate unknown) with inhibitor RO 8959	N/A	hiv82nci	SAIC, NCI Frederick	*	2002	RO 8959
HIV-1 PR (isolate unknown) with inhibitor RS 201	N/A	hiv83nci	SAIC, NCI Frederick	*	2002	RS 201
HIV-1 PR (isolate unknown) with inhibitor SB 107457	N/A	hiv84nci	SAIC, NCI Frederick	*	2002	SB 107457
HIV-1 PR (isolate unknown) with inhibitor RS 194	N/A	hiv85nci	SAIC, NCI Frederick	*	2002	RS 194
HIV-1 PR (isolate unknown) with inhibitor VA 77003	N/A	hiv86nci	SAIC, NCI Frederick	*	2002	VA 77003