SYSTEM	HIV-1 PR  (BH10 isolate) with hydroxyethylene inhibitor
HIVdb File	hiv3skb
PDB File	1aaq
Company or Laboratory	SmithKline Beecham Pharmaceuticals
Year	1992
INHIBITOR (Type)	SKB3_INH(hydroxyethylene isostere)
Composition of the Inhibitor (Substrate) or Summary Formula	Ala - Ala - Phe - psi (CHOH-CH2) - Ala - Val - Val - OMe
Resolution	2.5Ao
R factor	0.19
Space Group	P61
Dimension of Elementary Cell	a=63.30,b=63.30,c=83.60
a,b,g  (alpha,beta,gamma)	a=b=90.00,g=120.00
Reference	G.B.Dreyer, D.M.Lambert, T.D.Meek, T.J.Carr, T.A. Tomaszek, A.V.Fernandez, B.W.Metcal; Biochemistry, 31, 6646, 1992
Comment	Diffrence between Swiss-Prot and PDB sequence; SWISS-PROT: Leu131, Leu131   PDB SEQRES: Ile63 A, Ile63 B