| SYSTEM |
HIV-1
PR
(ARV2/SF2 isolate) (mutant)
complexed with a cyclic Phe-IleVal peptidomimetic inhibitor
|
| HIVdb File |
hiv2uba
|
| PDB File |
1mtr
|
| Company or Laboratory |
University of Queensland,Brisbane
AUSTRALIA
|
| Year |
1996
|
| INHIBITOR (Type) |
Phe-Ile-Val
(cyclic peptidomimetic
inhibitor)
|
| Composition of the Inhibitor
(Substrate) or Summary Formula |
N/A
|
| Schematic Formula |
Phe-Ile-Val
|
| Resolution |
1.75Ao
|
| R factor |
0.179
|
| Space Group |
P212121
|
| Dimension of Elementary
Cell |
a=51.40,b=58.70,c=62.00
|
| a,b,g
(alpha,beta,gamma)
|
a=b=g=90
|
| Reference |
D.R.March, G.Abbenante,
D.A.Bergman, R.I. Brinkworth, W.Wickramasinghe, J.Begun ,J.L.Martin, D.P.Fairlie;
to be published |
| Comment |
A cyclic Phe-Ile-Val inhibitor,
protease is mutated chain A,B, Q7K, L33I, C67(ABA), C95(ABA) |