| SYSTEM |
HIV-1
PR
(HXB2 isolate) C95A
mutant with DMP323 a novel cyclic urea-type inhibitor
|
| HIVdb File |
hiv2nid
|
| PDB File |
1bvg
|
| Company or Laboratory |
NIDR Bethesda
|
| Year |
1996
|
| INHIBITOR (Type) |
DMP323 (urea-type inhibitor)
|
| Composition of the Inhibitor
(Substrate) or Summary Formula |
C35H38N2O5
|
| Schematic Formula |
DMP323
|
| Resolution |
N/A
|
| R factor |
N/A
|
| Space Group |
N/A
|
| Dimension of elementary
cell |
N/A
|
| a,b,g
(alpha,beta,gamma)
|
N/A
|
| Reference |
T.Yamazaki, A.P.Hinck, Y.Wang,
L.K.Nicholson, D.A.Torchia, P.Wingfield, S.J.Stahl, J.D.Kaufman, C.Chang,
P.J.Domaille, P.Y.S.Lam; Protein
Science, 5, 495, 1996 |
| Comment |
HIV-1 PR-DMP323 complex
in solution, NMR minimized average structure, mutation C95A, expression
system BL21, expr.system - plasmid: pet11a |