| SYSTEM |
HIV-1
PR
(ARV2/SF2 isolate)
|
| HIVdb File |
hiv2nci
|
| PDB File |
3hvp
|
| Company or Laboratory |
ABL-BRP, NCI-FCRDC Frederick
|
| Year |
1989
|
| INHIBITOR (Type) |
N/A
|
| Composition of the Inhibitor
(Substrate) or Summary Formula |
N/A
|
| Schematic Formula |
N/A
|
| Resolution |
2.8Ao
|
| R factor |
0.184
|
| Space Group |
P41212
|
| Dimension of Elementary
Cell |
a=50.24,b=50.24,c=106.56
|
| a,b,g
(alpha,beta,gamma)
|
a=b=g=90
|
| Reference |
A.Wlodawer, M. Miller, M.
Jaskolski, B Sathya narayna, E. Baldwin, I.T. Weber, L.M.Selk, L. Clawson,
J.Schneider, S.B.H. Kent; Science,
245, 616, 1989 |
| Comment |
Amino acid sequence of HIV-1
PR (SF2 isolate) Cys67, Cys95 are replaced by Alpha - Amino - N - Butyric
Acid; residues differ from the NY5 isolate are R14K, K41R, P63L, V64I |