| SYSTEM |
HIV-1
PR
(BRU isolate) with allophenylnorstatine
inhibitor KNI-272
|
| HIVdb File |
hiv15nci
|
| PDB File |
1hpx
|
| Company or Laboratory |
SAIC, NCI-FCRDC Frederick
|
| Year |
1995
|
| INHIBITOR (Type) |
KNI-272 (allophenylnorstatine
analog)
|
| Composition of the Inhibitor
(Substrate) or Summary Formula |
(N - Tert - Butyl -
Thioproline) - (5 - Isoquinolyloxyacetyl - Methylthioalanine) - Allophenylnorstatine
|
| Schematic Formula |
KNI-272
|
| Resolution |
2Ao
|
| R factor |
0.17
|
| Space Group |
P212121
|
| Dimension of Elementary
Cell |
a=51.90,b=59.10,c=62.30
|
| a,b,g
(alpha,beta,gamma)
|
a=b=g=90
|
| Reference |
E.T.Baldwin, T.N.Bhat, B.Liu,
S. Gulnik, I.A.Topol, Y.Kiso, T. Mimoto, H.Mitsuya, J.W. Erickson;
Structure, 3, p581, 1995 |
| Comment |
The sequence in this entry
is 100% identical to that SwissProt entry POL_HV1BR which is for the BRU
isolate |