A full description of DNAWorks can be found in our recent publication (Hoover, D. and Lubkowski, J., 2002)

For further improvements in the performance of DNAWorks, feedback on the success or failure of gene synthesis using DNAWorks is very important. Please let us know about the outcome of your synthesis experiments.

Mutant Sequence

Generate new oligonucleotides to create mutants, using the parameters and overlap positions from a previous optimization

Enter a protein sequence Enter a DNA sequence Click here for help

Job name (required)

Job name:

You must enter a name for your job. Acceptable characters are [A-Za-z0-9_].

Mutant DNA Sequence

Enter mutant DNA sequence (formats)

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Upload mutant DNA sequence file (formats)

Original Logfile

Upload original logfile:

Trial Number

Trial to emulate:

E-mail Address (optional)

E-mail Address:

Entering your e-mail address is entirely voluntary. The results will be made available online at the end of the program run, but if an address is entered, the results will also be sent to that address.

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Comments/suggestions/errors to David Hoover

Center for Information Technology, National Institutes of Health
Last modified Nov. 28, 2004